Quinine is a medication used to treat malaria and babesiosis.
This includes the treatment of malaria due to Plasmodium falciparum that is resistant to chloroquine when artesunate is not available.
While used for restless legs syndrome, it is not recommended for this purpose due to the risk of side effects.
It can be taken by mouth or used intravenously.
Malaria resistance to quinine occurs in certain areas of the world.
Quinine is also the ingredient in tonic water that gives it its bitter taste.
Before taking this medicine
You should not use this medication if you have ever had an allergic reaction to quinine or similar medicines such as mefloquine or quinidine, or if you have:
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a heart rhythm disorder called Long QT syndrome;
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an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G-6-PD);
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myasthenia gravis;
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optic neuritis (inflammation of the optic nerve); or
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if you have taken quinine in the past and it caused a blood cell disorder, severe bleeding, or kidney problems.
To make sure quinine is safe for you, tell your doctor if you have:
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heart disease or a heart rhythm disorder;
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low levels of platelets in your blood;
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low potassium levels in your blood (hypokalemia); or
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liver or kidney disease.
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